good question
tile edit I don't know, I don't use it, but I would guess so - it's a very simple program...very
supposedly .38 allows for higher color depth in tilesets, but updating the client is not updating .lvl - there has been some concern on whether or not you CAN actually have a .lvl with a tileset that has more than 8-bit color depth
and of course higher color depths can often be very lag-enducing
I still haven't tested higher color depth tilesets on any maps yet, so I don't really know
I know Bob Dole.. Bob Dole... Bob Dole...... bob dole.... bob... dole.... said he tested his tileset changer and the map worked, but I also know someone else (Sass) did the same thing with FACTS (I think) and the map was not able to be used (replaced by defaultlevelfile when he tried to go to arena)